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Endpoint Clinical

Principal Software Engineer · 💰 $160,000–$170,000/year

North America

October 3, 2026 at 10:04 AM

✨ AI summary

💰 $160,000–$170,000/year

Location

  • United States

Languages

  • TypeScript
  • JavaScript (Node.js)
  • Rust
  • Go
  • C++

Frameworks

  • React

Cloud Services

  • Amazon Web Services (AWS)
  • Microsoft Azure

Experience Level

  • 12+ years
About Us

Endpoint is an interactive response technology (IRT®) systems and solutions provider that supports the life sciences industry. Since 2009, we have been working with a single vision in mind, to help sponsors and pharmaceutical companies achieve clinical trial success. Our solutions, realized through the proprietary PULSE® platform, have proven to maximize the supply chain, minimize operational costs, and ensure timely and accurate patient dosing. Endpoint is headquartered in Raleigh-Durham, North Carolina with offices across the United States, Europe, and Asia.

We ʼ re seeking a principal software engineer who is passionate, experienced and skilled, versatile, and customer-and business- oriented. In this role, we will also need someone who is full-stack and polyglot (see specific technologies below). This is a critical technical leadership role. As a principal engineer you will define the technical direction of our forecasting product, allowing us to scale and mentoring other engineers. You will also operate as a primary technical authority across multidisciplinary teams, partnering tightly with customers, partners and especially internal stakeholders, translating fundamental needs into technological solutions that drive the business.

Responsibilities

  • Partner closely with product and executive leadership to inform and implement company strategy. Work with internal stakeholders such as Product and UX to rapidly distill initially ambiguous requirements into concrete and actionable plans
  • Be a strong, hands-on contributor delivering code and features day-to-day
  • Drive technical strategy and architecture for our product across all engineering domains
  • Champion operational excellence: reliability, quality, and continuous risk reduction across the product. Document and oversee implementation of the engineering standards that ensure it.
  • Own the security and compliance posture appropriate our product, e.g. SOC 2,data integrity, and potentially GxP/21 CFR Part 11 consideration
  • Accelerate application development and uplevel engineering staff via mentorship and selecting relevant trainings, conferences, and events for the team
  • Help grow the team: interviewing, hiring, and raising the technical bar as we scale
  • Represent engineering with customers and other internal and external stakeholders
  • Be AI-literate, leveraging the latest technologies to inform the technical and
  • Product roadmap. You will educate internal stakeholders on how the latest technologies work and contribute key ideas to conversations about how they can be leveraged in the product

Experience

  • 12+ years of engineering excellence
  • A proven track record of architecting, scaling, and maintaining complex, scaled systems
  • Past responsibilities involve systems with large numbers of users in environments where quality, security, and reliability are critical
  • Polyglot mastery and a proven ability to learn new languages and architectures.
  • Ability to hit the ground running — someone who is already proficient in our current stack

Education

  • Bachelors degree or higher in Computer Science or other relevant field preferred

Skills Required

  • Should be expertise in front end technologies: TypeScript, React
  • Should have good experience in NodeJS
  • Rust ideally (ideally), or Go/C++
  • Amazon Web Services and Azure (ideally), or equivalent
  • CI/CD: GitHub Actions, or equivallent
  • Infrastructure-as-code solutions like Terraform, Pulumi or equivalent

$160,000 - $170,000 a year

Endpoint Clinical does not accept unsolicited resumes from search firms or any other third parties. Any unsolicited resume sent to Endpoint Clinical will be considered Endpoint Clinical property, and Endpoint Clinical will not pay a fee should it hire the subject of any unsolicited resume.

Endpoint Clinical is an equal opportunities employer AA/M/F/Veteran/Disability.

Pursuant to the San Francisco Fair Chance Ordinance, we will consider for employment, qualified applicants with arrest and conviction records.

We may use artificial intelligence (AI) tools to support parts of the hiring process, such as reviewing applications, analyzing resumes, or assessing responses and identifying potential inconsistencies or verification signals in application materials based on available information. These tools assist our recruitment team but do not replace human judgment. Final hiring decisions are ultimately made by humans. If you would like more information about how your data is processed, please contact us.